Diagnostic Tools for COVID-19

Objective: To review the current diagnostic methodology available for Coronavirus Disease 2019 (COVID-19) caused by new Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Method: This critically analyses merits and limitations of recent COVID-19 diagnostics being used disease prophylaxis its mitigation. Multiple research papers from 2019- 2022 were consulted. Many novel have been included, such as LAMP, CRISPR, AI other POC techniques, along with conventional RTPCR CT -SCAN. These compared based on principle, protocol, sensitivity, specificity, cost-effectiveness their pros cons. Findings: Mass Spectrometry Loop mediated isothermal amplification (LAMP) seen to be most sensitive specific. They also very rapid. However, is expensive, it requires sophisticated instrumentation. LAMP hand, does not require expensive machinery, thus a better choice. Novelty: has covered which earlier in reviews. We compiled all data one manuscript ease readers. talked about protocols made India sensitivities specificities. Keywords: COVID-19; Diagnostics; Coronavirus; Pandemic; Vaccine; Therapeutic